6-Azathymine - CAS:932-53-6

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6-Azathymine

目录号 : KM11370 CAS No. : 932-53-6 纯度 : 98%

Data Sheet 产品使用指南

6-Azathymine，胸腺嘧啶的 6-氮类似物，是一种有效的 D-3-氨基异丁酸酯-丙酮酸氨基转移酶 (D-3-aminoisobutyrate-pyruvate aminotransferase) 抑制剂。6-Azathymine 可抑制 DNA 的生物合成，并具有抗菌和抗病毒活性。

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生物活性	6-Azathymine, a 6-nitrogen analog of thymine, is a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor. 6-Azathymine inhibits the biosynthesis of DNA, and has antibacterial and antiviral activities.
体外研究	6-Azathymine is a competitive antagonist of the growth of Streptococcus faecalis (8043) and several other strains of microorganisms. Studies of the mechanism of action of 6-Azathymine reveal that S. faecalis can convert the analog to the corresponding deoxyriboside, azathymidine.
体内研究	The administration of 6-Azathymine to the mouse leads to the urinary elimination not only of free Azathymine, but also of various metabolites of it. Following the administration of 6-Azathymine-5-C to mice, radioactivity is found in all tissues investigated, not only in the form of free Azathymine, but also as metabolic derivatives.
分子式	C₄H₅N₃O₂
分子量	127.10
CAS号	932-53-6
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.