Tucotuzumab celmoleukin
(Synonyms:EMD 273066)
目录号 : KM32776
CAS No. : 339986-90-2
Tucotuzumab celmoleukin (EMD 273066) 是一种免疫细胞因子融合剂,靶向上皮细胞粘附分子 (EpCAM)。Tucotuzumab cellmoleukin 与 EpCAM 结合并将 IL-2 传递到肿瘤微环境,从而激活细胞毒性效应细胞,如 CD8+ T 细胞和自然杀伤 (NK) 细胞。Tucotuzumab cellmoleukin 有望用于 EpCAM 阳性癌症的研究,如结直肠癌和前列腺癌。
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| 生物活性 |
Tucotuzumab celmoleukin (EMD 273066) is an immunocytokine fusion agent targeting the epithelial cell adhesion molecule (EpCAM). Tucotuzumab celmoleukin binds to EpCAM and delivers IL-2 to the tumor microenvironment, which can activate cytotoxic effector cells, such as CD8+ T cells and natural killer (NK) cells. Tucotuzumab celmoleukin is promising for research of EpCAM-positive cancers, such as colorectal cancer and prostate cancer.
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| CAS号 |
339986-90-2
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| 中文名称 |
Tucotuzumab Celmoleukin
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
| Powder |
-20°C |
3 years |
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4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
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