Dibenzothiophene-d8
(Synonyms:二苯并噻吩同位素-D8;氘代二苯并噻吩;二苯并噻吩-d8)
目录号 : KM33188
CAS No. : 33262-29-2
Dibenzothiophene-d8 是 Dibenzothiophene 的氘代物。 Dibenzothiophene 是一种口服活性的非竞争性 CYP1A 抑制剂。Dibenzothiophene 抑制 CYP1A 介导的 EROD 活性,Km 为 0.592 μM。Dibenzothiophene 与 AHR 通路相互作用。Dibenzothiophene 增强 β-naphthoflavone 的胚胎毒性。Dibenzothiophene 对小鼠有急性毒性。Dibenzothiophene 主要用于研究生物体发育毒性的机制。
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| 生物活性 |
Dibenzothiophene-d8 is the deuterium labeled Dibenzothiophene . Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with Km of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone . Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms.
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| 分子式 |
C12D8S
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| 分子量 |
192.31
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| CAS号 |
33262-29-2
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| 中文名称 |
二苯并噻吩-d8
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
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