Rademikibart (Synonyms:乐德奇拜单抗)
目录号 : KM33424 CAS No. : 2648260-80-2 纯度 : 98%
Rademikibart (CBP-201) 是一种靶向 IL-4Rα 的人单克隆抗体,与人 IL-4Rα 表位结合时的 KD 为 20.7 pM。Rademikibart 不与其他物种的 IL-4Rα 结合。Rademikibart 抑制 PBMC 中 IL-4 和 IL-13 介导的 STAT6 信号传导、TF-1 细胞增殖和 TARC 产生。Rademikibart 具有用于中重度 Th2 炎症性疾病研究的潜力。
规格 价格 是否有货 数量
1mg
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Other Forms of Rapamycin:

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生物活性
Rademikibart (CBP-201) is a human monoclonal antibody targeting IL-4Rα with a KD of 20.7 pM when binding to human IL-4Rα epitopes. Rademikibart does not bind to IL-4Rα from other species. Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation and TARC production in PBMCs. Rademikibart has the potential for moderate-to-severe Th2 inflammatory diseases research.
分子量
145.36 kDa
CAS号
2648260-80-2
运输条件
Shipping with dry ice.
储存方式
Store at -20˚C 
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