LacCer (d18:1/16:0)-d3 (Synonyms:氘代棕榈酰-(甲基D3)-乳糖基酰基鞘胺醇)
目录号 : KM35249 CAS No. : 2097249-92-6
LacCer (d18:1/16:0)-d3 (C16 Lactosylceramide (d18:1/16:0)-d3) 是氘标记的 LacCer (d18:1/16:0) 。LacCer (d18:1/16:0) 是一种内源性生物活性鞘糖脂,可与 Lyn 激酶和抑制性 G 蛋白偶联受体 (GPCRs) 的 αi 亚单位形成膜微区。LacCer (d18:1/16:0) 水平会在在胰岛素抵抗性的牛血浆中升高。在小鼠的尼曼匹克 C1 型病 (一种神经退行性胆固醇-鞘糖脂溶酶体储存病) 模型中,LacCer (d18:1/16:0) 的表达也被上调。LacCer (d18:1/16:0) 可用于代谢疾病与神经退行性疾病领域的研究。
规格 价格 是否有货 数量
1mg
In-stock
5mg 询价 In-stock
10mg 询价 In-stock

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生物活性
LacCer (d18:1/16:0)-d3 (C16 Lactosylceramide (d18:1/16:0)-d3) is the deuterium labeled LacCer (d18:1/16:0) . LacCer (d18:1/16:0) is an endogenous bioactive sphingolipid that can form membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs). The levels of LacCer (d18:1/16:0) are elevated in the plasma of insulin-resistant cattle. In a mouse model of Niemann-Pick type C1 disease (a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder), the expression of LacCer (d18:1/16:0) is also upregulated. LacCer (d18:1/16:0) can be used in research on metabolic diseases and neurodegenerative diseases.
分子式
C46H84D3NO13
分子量
865.2
CAS号
2097249-92-6
中文名称
棕榈酰-(甲基-D3)-乳糖神经酰胺
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2