PROTACs SMARCA2/4-degrader-9
目录号 : KM36178 CAS No. : 2568507-15-1
PROTACs SMARCA2/4-degrader-9 (Compound I-503) 是一种 PROTACs 降解剂,用于 SWI/SNF 复合体的催化亚基 SMARCA2 和 SMARCA4。PROTACs SMARCA2/4-degrader-9 在 MV411 和 A549 中降解 SMARCA2,DC50 <100 nM;在 MV411 中降解 SMARCA4,DC50 <100 nM。(粉色:靶蛋白配体 ;黑色:连接子 ;蓝色:E3 连接酶配体 (S,R,S)-AHPC )
规格 价格 是否有货 数量

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生物活性
PROTACs SMARCA2/4-degrader-9 (Compound I-503) is a PROTACs degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTACs SMARCA2 degrader-9 degrades SMARCA2 in MV411 and in A549 with DC50 <100 nM, degrades SMARCA4 in MV411 with DC50 <100 nM. (Pink: Ligand for target protein ; Black: Linker ; Blue: Ligand for E3 ligase (S,R,S)-AHPC )
分子式
C49H59N11O5S
分子量
914.13
CAS号
2568507-15-1
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2