| 生物活性 |
Ontorpacept (TTI-621) is a soluble fusion protein that consists of the human SIRPα N-terminal (1-118) linked to the Fc region of human IgG1. The N-terminal (1-118)-fragment of ontorpacept is a binding domain for CD47 which is an inhibitor of phagocytosis by macrophages. Ontorpacept is a CD47-blocking checkpoint inhibitor with antitumor activity.
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| 分子量 |
76.43 kDa
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| CAS号 |
2131089-46-6
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| 运输条件 |
Shipping with dry ice.
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| 储存方式 |
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纯度： 99%
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Data Sheet
