Anetumab ravtansine (Synonyms:雷星-阿奈妥单抗)
目录号 : KM37423 CAS No. : 1375258-01-7
Anetumab ravtansine (BAY 94-9343) 是一种靶向抗有丝分裂蛋白 (maytansinoid) 微管蛋白 (tubulin) 的抗体药物偶联物 (ADC),效力强、具有选择性。Anetumab ravtansine 由 maytansoid 微管蛋白抑制剂 DM4 偶联人抗间皮素抗体组成。Anetumab ravtansine 在患者源性异种移植瘤模型中显示抗肿瘤药效,其效力与在间皮素表达量相关。
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生物活性
Anetumab ravtansine (BAY 94-9343) is a selective and highly potent antibody-drug conjugate (ADC) to target maytansinoid tubulin. Anetumab ravtansine consists of a human anti-mesothelin antibody conjugated to the maytansinoid tubulin inhibitor DM4. Anetumab ravtansine shows antitumor efficacy correlated with the amount of mesothelin expressed in patient-derived xenograft tumor models.
CAS号
1375258-01-7
中文名称
Anetumab Ravtansine
运输条件
Shipping with dry ice.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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