Simvastatin acid-d6
目录号 : KM37977
CAS No. : 2747915-75-7
Simvastatin acid-d6 (Tenivastatin-d6) 是氘代标记的 Simvastatin acid. Simvastatin acid (Tenivastatin),Simvastatin 的水解产物,是一种有效的 HMG-CoA 还原酶 (HMGCR) 抑制剂。Simvastatin acid 降低吲哚酚硫酸盐 (Indoxyl sulfate) 介导的活性氧 (ROS) 产生。Simvastatin acid 也可调节心肌细胞和转染 OATP3A1 基因的 HEK293 细胞的 OATP3A1 表达。
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| 生物活性 |
Simvastatin acid-d6 (Tenivastatin-d6) is deuterium labeled Simvastatin acid. Simvastatin acid (Tenivastatin), a hydrolysate of Simvastatin , is a HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.
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| 分子式 |
C25H34D6O6
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| 分子量 |
442.62
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| CAS号 |
2747915-75-7
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
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-20°C |
1 month |
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