BI-765423 - KKL Med Inc.

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BI-765423

目录号 : KM32548 纯度 : 95%

Data Sheet 产品使用指南

BI-765423 是针对 IL-11 的选择性单克隆抗体抑制剂。BI-765423 可阻断 IL-11 介导的信号传导，抑制成纤维细胞活化，同时可延长哺乳动物健康寿命、对抗人类细胞的衰老转化，减轻炎症衰老相关病理进程。BI-765423 主要用于特发性肺纤维化 (IPF) 等纤维化疾病的研究。

规格	价格	是否有货	数量
1mg		In-stock

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生物活性	BI-765423 is a selective monoclonal antibody inhibitor targeting IL-11. BI-765423 blocks IL-11-mediated signaling, inhibits fibroblast activation, and can extend the healthy lifespan of mammals, counteract cellular senescence in human cells, and alleviate inflammatory aging-related pathological processes. BI-765423 is primarily used in research on fibrotic diseases such as idiopathic pulmonary fibrosis (IPF).
体外研究	BI-765423 can significantly inhibit fibroblast activation and reduce the progression of inflammation and aging related pathological processes in human fibroblast in vitro experiments. BI-765423 can effectively resist the aging transformation of human cells in vitro and play a potential anti-aging activity.
体内研究	BI-765423 can prolong the healthy lifespan of mammals by inhibiting IL-11 signaling and has inhibitory effects on the pathological processes associated with idiopathic pulmonary fibrosis (IPF).
分子量	146.61 kDa
运输条件	Shipping with dry ice.
储存方式	Store at -80°C for 2 years. Aliquots should be stored at the same temperature after first use to avoid multiple freeze-thaws