Sulfaclozine sodium (Synonyms:Sulfachloropyrazine sodium)
目录号 : KM12888 CAS No. : 23307-72-4 纯度 : 98%

Sulfaclozine sodium (Sulfachloropyrazine sodium) 是一种有效的磺酰胺衍生物,具有抗菌和抗球虫作用。Sulfaclozine sodium 通常用于各种家禽疾病(尤其是结肠杆菌病,禽霍乱和球虫病)的相关研究。

规格 价格 是否有货 数量
100mg
In-stock
200mg 询价 In-stock
500mg 询价 In-stock

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生物活性

Sulfaclozine sodium (Sulfachloropyrazine sodium) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).

体外研究

The elimination of Sulfaclozine in the three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8. Sulfaclozine is weakly adsorbed on the surface of TiO2 at pH 7 (< 5%) but efficiently eliminated with the following three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8 in ultra pure water. Moreover, 12 of Sulfaclozine by-products are identified and reaction pathways show that, in addition of OH and SO4 radicals, the conduction-band electrons are responsible for the formation of some main by-products either directly or by the formation of superoxide radicals.

体内研究

Sulfaclozine (60 mg/kg; intravenous injection or oral administration; male broiler chickens) can be used primarily for the treatment of parasitic and microbial infections of the digestive tract rather than for the treatment of systemic infections.

Animal Model: 14 male broiler chickens (30-day-old)
Dosage: 60 mg/kg
Administration: Intravenous injection or oral administration (Pharmacokinetic Analysis)
Result: Serum drug concentrations at 0.083, 0.50, 2, 6, 24 and 72h were determined to be 99.62, 83.50, 72.68, 58.43, 38.66 and 13.14 μg/mL, respectively, by intravenous injection. By oral administration were determined as 4.33, 7.95, 16.46, 22.88, 16.03 and 5.74 μg/mL, respectively.
分子式
C10H8ClN4NaO2S
分子量
306.70
CAS号
23307-72-4
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O : 50 mg/mL (163.03 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.2605 mL 16.3026 mL 32.6051 mL
5 mM 0.6521 mL 3.2605 mL 6.5210 mL
10 mM 0.3261 mL 1.6303 mL 3.2605 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

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