Dequalinium氯化物是apamin敏感型的钾离子通道选择性阻断剂。
| 生物活性 |
Dequalinium Chloride is a selective blocker of apamin-sensitive K+ channels. Target: Potassium Channel Dequalinium Chloride is a selective blocker of apamin-sensitive K+ channels. Treatment with Dequalinium chloride did not influence conditions caused by haemolytic streptococci -- verified by bacteriological examinations of pharyngeal smears -- inspite of its efficiency in vitro [1]. Dequalinium chloride (DECA), a cationic, lipophilic mitochondrial poison, selectively targets the mitochondrial membrane of certain epithelial carcinoma cells, in which it inhibits cellular energy production. Higher DECA doses under either regimen induced severe toxic effects and mortality [2]. |
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| 分子式 |
C30H40Cl2N4
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| 分子量 |
527.57
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| CAS号 |
522-51-0
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| 中文名称 |
地喹氯铵；地喹氯胺；克菌定
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 溶解性数据 |
In Vitro:
DMSO : < 1 mg/mL (insoluble or slightly soluble) Ethanol : < 1 mg/mL (insoluble) H2O : < 0.1 mg/mL (insoluble) |
纯度： 98%
客服小K 
客服小K
Data Sheet
