Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.
体内研究
Thymidine (500 mg/kg; i.p.; twice a day) completely reverses both Methotrexate- and Tomudex-induced deletion of both CD4Vβ8 and CD8Vβ8 T cells .
Animal Model:
8-12 weeks BALB/c mice
Dosage:
500 mg/kg
Administration:
i.p.; twice a day
Result:
Completely abrogates Methotrexate- and Tomudex-induced deletion of Vβ8 T cells after SEB injection.
分子式
C10H14N2O5
分子量
242.23
CAS号
50-89-5
运输条件
Room temperature in continental US; may vary elsewhere.