Secukinumab (AIN457) is a high affinity, human monoclonal antibody targeted against interleukin (IL)-17A. Secukinumab is the first-in-class anti-IL-17 agent used for the research of plaque psoriasis, ankylosing spondylitis and psoriatic arthritis.
体外研究
Secukinumab is a fully human monoclonal antibody that selectively binds to and neutralizes interleukin-17A.
Secukinumab (1 nM, 10 nM, and 100 nM) inhibits IL17A and IL17A/TNF a-induced increase in protein levels of IL6 in human astrocytes.
分子量
144 kDa
CAS号
1229022-83-6
中文名称
苏金单抗;司库奇尤单抗
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.