Abiraterone-D4 - CAS:2122245-62-7

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Abiraterone-D4 (Synonyms:(CB-7598-d4))

目录号 : KM16700 CAS No. : 2122245-62-7 纯度 : 98%

Data Sheet 产品使用指南

Abiraterone-D4 (CB-7598-D4) 是 Abiraterone 的氘代物。Abiraterone 是一种有效的不可逆的 CYP17A1 抑制剂，具有抗雄激素活性，抑制细胞色素 p450 酶 CYP17 的 17α-羟化酶和 17,20-裂合酶活性，IC₅₀ 值分别为 2.5 nM 和 15 nM.

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1mg		In-stock

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生物活性	Abiraterone-D4 (CB-7598-D4) is the deuterium labeled Abiraterone. Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC₅₀s of 2.5 nM and 15 nM, respectively.
体外研究	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
分子式	C₂₄H₂₇D₄NO
分子量	353.53
CAS号	2122245-62-7
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.