Disopyramide-d14 tosylate salt - CAS:1216989-88-6

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Disopyramide-d14 tosylate salt

目录号 : KM3078 CAS No. : 1216989-88-6

Data Sheet 产品使用指南

Disopyramide-d14 (Dicorantil-d14) tosylate salt 是 Disopyramide 的氘代物。Disopyramide (Dicorantil) 是一种用于研究室性和房性心律失常的 IA 类抗心律失常试剂。Disopyramide 阻断心肌快速内向钠电流 (sodium current)，延长心肌动作电位持续时间。Disopyramide 抑制 HERG 编码的钾通道 (potassium channels)。Disopyramide 也表现出复杂的蛋白质结合，并具有强大的负性肌力作用。

规格	价格	是否有货	数量
1mg	询价	In-stock
10mg	询价	In-stock

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生物活性	Disopyramide-d14 (Dicorantil-d14) tosylate salt is the deuterium labeled Disopyramide. Disopyramide (Dicorantil) is a class IA antiarrhythmic drug with efficacy in ventricular and atrial arrhythmias. Disopyramide blocks the fast inward sodium current of cardiac muscle and prolongs the duration of cardiac action potentials. Disopyramide inhibits HERG encoded potassium channels. Disopyramide also exhibits complex protein binding, and has a potent negative inotropic action.
体外研究	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
分子式	C₂₁H₂₉N₃O^.C₇H₈O₃S
分子量	525.76
CAS号	1216989-88-6
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.