Antipain dihydrochloride是一种从 Actinomycetes 分离的蛋白酶 (protease) 抑制剂。Antipain dihydrochloride 抑制 N-甲基-N'-硝基-N-亚硝基胍 (MNNG) 诱导的转化，增加染色体畸变。Antipain dihydrochloride 限制小鼠中子宫 DNA 合成和功能。
| 生物活性 |
Antipain dihydrochloride is a protease inhibitor isolated from Actinomycetes. Antipain dihydrochloride inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride restricts uterine DNA synthesis and function in mice. |
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| 体内研究 |
The intact, cycling female mice received subcutaneous injections of Antipain dihydrochloride (3 mg) for 16 days, their uteri shows significant diminution in weight and total DNA when compared to untreated controls.
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| 分子式 |
C27H44N10O6.2[HCl]
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| 分子量 |
677.62
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| CAS号 |
37682-72-7
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 临床试验 |
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纯度： ≥95%
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