Mycophenolic Acid β-D-Glucuronide
(Synonyms:霉酸β-D -葡萄糖醛酸;霉酚酸-D -葡萄糖醛酸苷标准品;霉酚酸-D3-β-D-葡糖苷酸;霉酚酸-β-D-葡糖苷酸;霉酚酸-β-D-葡糖苷酸 标准品;霉酚酸葡糖苷酸)
目录号 : KCM13276
CAS No. : 31528-44-6
纯度 : ≥98%
Mycophenolic acid β-D-glucuronide (MPAG) is a metabolite of the immunosuppressant mycophenolic acid . It is formed from mycophenolic acid by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A9, UGT1A8, UGT1A7, and UGT1A10 in insect cell-derived supersomes expressing the human enzymes. Unlike mycophenolic acid, MPAG does not inhibit IMP dehydrogenase (IMPDH) type II in a cell-free assay. However, it does reduce tumor growth in an Ehrlich murine spontaneous adenocarcinoma model when administered at a dose of 6 mg/animal.
Other Forms of Rapamycin:
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| 分子式 |
|
| 分子量 |
496.5
|
| CAS号 |
31528-44-6
|
| 中文名称 |
霉酚酸葡糖苷酸
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|