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Koningic acid
目录号 : KF1093 CAS No. : 74310-84-2 纯度 : 95%
Data Sheet 产品使用指南
Koningic acid (KA; 74310-84-2) is a potent and selective inhibitor of glyceraldehyde-3-phosphate dehydrogenase (GAPDH).  Inhibition is irreversible and proceeds via nucleophilic attack of an active site cysteine on the epoxide moiety, Ki = 1.1 μM for rabbit muscle GAPDH. KA can selectively kill high-glycolytic cancer cells via glucose dependent ATP depletion. Has been used in a predictive model for selective targeting of the Warburg effect, the most prominent hallmark of cancer cell metabolism.
规格 价格 是否有货 数量
1mg
In-stock
2.5mg
In-stock
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分子式
C15H20O5
分子量
280.32
CAS号
74310-84-2
中文名称
Heptelidic acid
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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