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ZJ43 (Synonyms:N-{[(1S)-1-羧基-3-甲基丁基]氨基甲酰}-L-谷氨酸;富马酸单乙基酯钙盐)
目录号 : KF1101 CAS No. : 723331-20-2 纯度 : 98%
Data Sheet 产品使用指南
ZJ43 (723331-20-2) is potent inhibitor of glutamate carboxypeptidases II (Ki = 0.8 nM) and III (Ki = 23 nM). It potently (IC50 = 2.4 nM) inhibited the ability of glutamate carboxypeptidase II to hydrolyze the neurotransmitter N-acetylaspartylglutamate (NAAG) resulting in an increase in synaptic levels of group II mGluRs. Peripherally administered ZJ43 increased the activation of mGluR3 by NAAG released from peripheral sensory neurites resulting in analgesia. ZJ43 has also shown efficacy in other inflammatory pain models.
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5mg
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25mg
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分子式
C12H20N2O7
分子量
304.3
CAS号
723331-20-2
中文名称
富马酸单乙基酯钙盐
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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