MC-DM1 是由 linker MC 和 毒性分子 DM1 连接而成的,可用来制备抗体偶联药物。DM1 (Mertansine),是含硫醇的美登木素生物碱,是一种有效的微管破坏剂。
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MC-DM1 is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker MC to make antibody drug conjugate (ADC).
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