Apatinib - Apatinib mesylate | YN968D1 | Rivoceranib mesylate (Synonyms:N-[4-(1-氰基环戊基)苯基]-2-[(4-吡啶甲基)氨基]-3-吡啶甲酰胺甲磺酸盐;甲磺酸阿帕替尼)
目录号 : KA1155 CAS No. : 1218779-75-9 纯度 : 98%
Potent and selective inhibitor of VEGFR2 tyrosine kinase (IC50 value of 1 nM). Apatinib could also potently suppress the activities of RET, c-KIT and c-Src with IC50 values of 0.13, 0.429 and 0.53 μM, respectively. In vivo, apatinib alone and in combination with chemotherapeutic agents effectively inhibited the growth of several established human tumor xenograft models with little toxicity.
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10mg
In-stock
50mg
In-stock
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分子式
C25H27N5O4S
分子量
493.58
CAS号
1218779-75-9
中文名称
N-[4-(1-氰基环戊基)苯基]-2-[(4-吡啶甲基)氨基]-3-吡啶甲酰胺甲磺酸盐
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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