Locostatin - UIC 1005
(Synonyms:(4S)-N-巴豆酰基-4-异丙基-2-恶唑烷酮;(N-巴豆)-(4s)-异丙基-2-噁唑烷酮)
目录号 : KA1579
CAS No. : 90719-30-5
纯度 : 97%
Non-toxic Raf kinase inhibitory protein (RKIP) inhibitor; disrupts the interaction of RKIP, not only with Raf-1 kinase, but also with GRK2; Locostatin is an inhibitor of cell sheet migration and cell growth in an epithelial cell proliferation assay, and it induced T cell anergy by blocking cytokine production after Ag recall. Other evidence suggested that Locostatin’s effects on cytoskeletal structure and migration are caused through mechanisms independent of its binding to RKIP and Raf/MAP kinase signaling.
Other Forms of Rapamycin:
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| 分子式 |
C14H15NO3
|
| 分子量 |
245.27
|
| CAS号 |
90719-30-5
|
| 中文名称 |
(N-巴豆)-(4s)-异丙基-2-噁唑烷酮
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|