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AR-42 (Synonyms:(11BETA,17ALPHA)-11,17-二羟基-3-氧代雄甾-1,4-二烯-17-羧酸;(S)-(+)-N-羟基-4-(3-甲基-2-苯基丁酰氨基)苯甲酰胺;AR-42 抑制剂)
目录号 : KA1598 CAS No. : 935881-37-1 纯度 : 98%
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AR-42 is a novel HDAC inhibitor (IC50 value of 16 nM) with potent anticancer effects in pancreatic cancer cells at submicromolar concentrations by inducing cell cycle arrest, stimulating apoptosis, and regulating expression of several miRNAs. Also demonstrated anticancer activity in many other cancers, including acute myeloid leukemia, multiple myeloma, prostate cancer, ovarian cancer, human glioma cells, and bladder cancer.
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分子式
C18H20N2O3
分子量
312.36
CAS号
935881-37-1
中文名称
AR-42 抑制剂
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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