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9-Methoxyellipticine
目录号 : KCM10132 CAS No. : 10371-86-5 纯度 : ≥95%
Data Sheet 产品使用指南
9-Methoxyellipticine is an alkaloid and a derivative of the DNA intercalating agent ellipticine that has been found in O. maculata and has anticancer activity. It intercalates into DNA and is an inhibitor of wild-type c-Kit and c-Kit containing the D816V activating mutation (c-Kit; ICs = 0.8 and 0.6 µM, respectively). 9-Methoxyellipticine inhibits proliferation of Ba/F3 cells in the presence of the c-Kit ligand SCF and Ba/F3 cells expressing c-Kit (ICs = 0.5 and 0.3 µM, respectively). It also increases survival in a variety of rodent tumor models.
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1mg
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5mg
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分子式
C18H16N2O
分子量
276.33252
CAS号
10371-86-5
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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