| 生物活性 |
(2S)-OMPT (triethylamine), Lysophosphatidic acid analogue, is a LPA3 G-protein-coupled receptor agonist. (2S)-OMPT (triethylamine) selectively activates LPA3 G-protein-coupled receptor to trigger downstream cellular signaling events. (2S)-OMPT (triethylamine) induces calcium, IL-6 release in cancer cells and activates MAPK and Akt signaling pathways. (2S)-OMPT (triethylamine) can be used for the research of ovarian cancer. |
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| 体外研究 |
(2S) - OMPT (0.001-10000 nM) (triethylamine) can induce the release of calcium ions from human ovarian cancer cell line OVCAR3, with an EC50 of 9.0 nM. (2S) - OMPT (0.01-1 μM) (triethylamine) can activate the phosphorylation of Akt and MAPK in human ovarian cancer OVCAR3 cells. (2S) - OMPT (0.01-10 μM) (triethylamine) can induce the release of IL-6 in human ovarian cancer cell line OVCAR3. |
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| 分子式 |
C22H43O6PS.2(C2H5)3N
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| 分子量 |
669
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| CAS号 |
1217471-69-6
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| 中文名称 |
(2S)-OMPT (三乙胺)
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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纯度： ≥98%
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