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(R)-nitro-Blebbistatin
目录号 : KCM10686 CAS No. : 1217619-62-9 纯度 : ≥98%
Data Sheet 产品使用指南
(R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin , which is the inactive form of (–)-blebbistatin . Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R)-nitro-Blebbistatin has the same stereochemistry as the inactive (+)-blebbistatin enantiomer.
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生物活性

(R)-nitro-Blebbistatin is an analog of (-)-Blebbistatin. (-)-Blebbistatin is a selective non-muscle myosin II inhibitor.
分子式
C17H13N3O4
分子量
323.3
CAS号
1217619-62-9
中文名称
R-(-)-7-Desmethyl-8-nitro blebbistatin
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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