Araguspongin B
目录号 : KCM10751
CAS No. : 123000-02-2
纯度 : ≥90%
Xestospongins and araguspongins are marine natural products first isolated from Pacific basin sponges, and noted to have vasodilatory properties. Inositol phosphates (IP) are important signal transduction messengers acting via IP receptors to promote the mobilization of Ca from intracellular stores. Araguspongin B antagonizes the calcium-releasing action of inositol 1,4,5-trisphosphate at the receptor level in cerebral microsomes, with an IC of 0.6 µM. It is nearly as potent as xestospongin C as an antagonist of the IP receptor.
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| 分子式 |
C28H50N2O2
|
| 分子量 |
446.7
|
| CAS号 |
123000-02-2
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|