Tolvaptan-d7 (Synonyms:托伐普坦 d7)
目录号 : KCM10822 CAS No. : 1246818-18-7 纯度 : 98%
Tolvaptan-d is intended for use as an internal standard for the quantification of tolvaptan by GC- or LC-MS. Tolvaptan is a nonpeptide vasopressin V receptor antagonist (IC = 3 nM for rat receptor) and a diuretic agent. It is selective for V over V receptors (IC = 0.58 μM). Tolvaptan increases urine volume by 3-fold in rats when administered at a dose of 0.54 mg/kg. It also reduces left ventricular end-systolic volumes and improves left ventricular ejection fraction in a rat model of myocardial infarction. Formulations containing tolvaptan have been used to treat hyponatremia.
规格 价格 是否有货 数量
500μg
In-stock
1mg
In-stock
5mg
In-stock

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生物活性

Tolvaptan-d7 is the deuterium labeled Tolvaptan. Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation.

分子式
C26H18ClD7N2O3
分子量
455.9835
CAS号
1246818-18-7
中文名称
托伐普坦 d7
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2