L-Valacyclovir-d8 (hydrochloride)
(Synonyms:盐酸万乃洛韦-D8氘代内标;伐昔洛韦-d8盐酸盐(L-缬氨酸-d8);哌嗪-1-羧酸苄酯;万乃洛韦-D8盐酸;盐酸万乃洛韦-D8)
目录号 : KCM10915
CAS No. : 1279033-32-7
纯度 : 98%
L-Valacyclovir-d is intended for use as an internal standard for the quantification of L-valacyclovir by GC- or LC-MS. L-Valacyclovir is an L-valyl prodrug form of the antiviral guanosine analog acyclovir . L-Valacyclovir inhibits herpes simplex virus type 1 (HSV-1) replication (IC = 0.84 µM in Vero cells). It is more potent than the stereoisomer D-valacyclovir but less potent than acyclovir in vitro, however, it is rapidly converted to acyclovir in vivo. Formulations containing L-valacyclovir have been used in the treatment of HSV-1 infections.
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| 分子式 |
C13H12D8N6O4.HCl
|
| 分子量 |
332.38442
|
| CAS号 |
1279033-32-7
|
| 中文名称 |
盐酸万乃洛韦-D8氘代内标
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|