Padanamide A is a bacterial metabolite originally isolated from a marine Streptomyces species. It is active against five strains of P. falciparum (ECs = 160-340 nM), is not cytotoxic to HEK293 or HepG2 human cell lines, but is cytotoxic to Jurkat T lymphocytes with an IC value of approximately 60 µg/ml.
Padanamide A is a linear tetrapeptide without proteinogenic amino acids. Padanamide A has the activity of inhibiting the biosynthesis of cysteine and methionine.
分子式
C31H47N7O9
分子量
661.8
CAS号
1314881-80-5
运输条件
Room temperature in continental US; may vary elsewhere.