(S)-WAY-100135 (hydrochloride) (Synonyms:(alphaS)-N-叔丁基-4-(2-甲氧基苯基)-alpha-苯基-1-哌嗪丙酰胺二盐酸盐)
目录号 : KCM11545 CAS No. : 149007-54-5 纯度 : ≥98%
(S)-WAY-100135 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT (IC = 15.5 nM in a radioligand binding assay using rat hippocampus). It is selective for 5-HT over 5-HT, 5-HT, and 5-H receptors, as well as dopamine D and D, and α-, α-, and β-adrenergic receptors (ICs = >1 µM for all). (S)-WAY-100135 (10 mg/kg) increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity.
规格 价格 是否有货 数量
5mg
In-stock
10mg
In-stock

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生物活性

(S)-WAY 100135 dihydrochloride is a highly selective and potent antagonist of 5-HT 1A (IC50=33.9 nM). (S)-WAY 100135 dihydrochloride has anxiolytic activity in animal models.

分子式
C24H33N3O2.2HCl
分子量
468.46
CAS号
149007-54-5
中文名称
(2S)-3-[4-(2-Methoxyphenyl)-1-piperazinyl]-N-(2-methyl-2-propanyl )-2-phenylpropanamide dihydrochloride
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

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The dilution calculator equation
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This equation is commonly abbreviated as: C1V1 = C2V2