15-deoxy-Δ12,14-Prostaglandin J2-d4 - CAS:1542166-82-4

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15-deoxy-Δ12,14-Prostaglandin J2-d4 (Synonyms:15d-PGJ2-d4; 15-Deoxy-Δ12,14-PGJ2-d4)

目录号 : KCM11640 CAS No. : 1542166-82-4 纯度 : 98%

Data Sheet 产品使用指南

15-deoxy-Δ-PGJ-d contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 15-deoxy-Δ-PGJ by GC- or LC-mass spectrometry. 15-deoxy-Δ-Prostaglandin J (15-deoxy-Δ-PGJ) is a metabolite of PGJ 15-deoxy-Δ-PGJ is formed from PGD by the elimination of two molecules of water. It binds selectively to PPARγ with an EC of 2 µM in a murine chimera system. 15-deoxy-Δ-PGJ is more potent than PGD, Δ-PGJ, and PGJ in stimulating lipogenesis in C3H10T1/2 cells. The EC for induction of adipocyte differentiation in cultured fibroblasts is 7 µM.

规格	价格	是否有货	数量
25μg		In-stock
50μg		In-stock
100μg		In-stock

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生物活性

15-deoxy-Δ12,14-Prostaglandin J2-d4 is the deuterium labeled 15-Deoxy-Δ-12,14-prostaglandin J2. 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM.

分子式

C₂₀H₂₄D₄O₃

分子量

320.46

CAS号

1542166-82-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： 98%

Data Sheet

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