1,4-PBIT (dihydrobromide) (Synonyms:1,4-PB-ITU 二氢溴酸盐)
目录号 : KCM11715 CAS No. : 157254-60-9 纯度 : ≥98%
1,4-PBIT is a potent inhibitor of purified human iNOS and nNOS with K values of 7.4 and 16 nM, respectively, compared to a K of 360 nM for human eNOS. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.
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生物活性

1,4-PBIT (dihydrobromide) is a potent nitric oxide synthases (NOS) inhibitor, with Ki values of 7.6 nM, 360 nM, and 16 nM for the inducible (iNOS), endothelial (eNOS), and neuronal (nNOS) isozymes, respectively.

分子式
C12H18N4S2.2HBr
分子量
444.2
CAS号
157254-60-9
中文名称
1,4-PB-ITU 二氢溴酸盐
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

The molarity calculator equation
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2