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CRANAD 28
目录号 : KCM11819 CAS No. : 1623747-97-6 纯度 : ≥98%
Data Sheet 产品使用指南
CRANAD 28 is a curcumin derivative and non-conjugated fluorescent affinity probe for the detection of amyloid-β (Aβ) in vitro and in vivo that has excitation/emission spectra of 498/578 nm, respectively. It binds to various forms of Aβ, including Aβ40 monomers and aggregates, as well as Aβ42 monomers, dimers, and oligomers (Ks = 68.8, 52.4, 159.7, 162.9, and 85.7 nM, respectively). When bound to Aβ, the fluorescence intensity decreases, in contrast to similar curcumin-based fluorescent probes. CRANAD 28 labels amyloid plaques and cerebral amyloid angiopathy both in APP/PS1 mouse brain sections and in live mice following i.v. administration. It also inhibits copper-induced and naturally occurring Aβ crosslinking.
规格 价格 是否有货 数量
500μg
In-stock
1mg
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5mg
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10mg
In-stock
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分子式
C27H23BF2N4O2
分子量
484.3
CAS号
1623747-97-6
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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