Epiblastin A - CAS:16470-02-3

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Epiblastin A

目录号 : KCM11870 CAS No. : 16470-02-3 纯度 : ≥98%

Data Sheet 产品使用指南

Epiblastin A is an ATP-competitive inhibitor of the casein kinase 1 (CK1) isoforms α, δ, and ε (ICs = 8.9, 0.5, and 4.7 μM, respectively). It is selective for CK1α, CK1δ, and CK1ε at concentrations below 10 μM, however, it also inhibits BRSK1, EEF2K, EGFR, MNK-2, and RIPK2 (ICs = 24-45 μM). Epiblastan A reduces immunoprecipitation of CK1α, CK1δ, and CK1ε from HCT116 cell lysates in a concentration-dependent manner. It induces reprogramming of mouse epiblast stem cells (mEpiSCs) into embryonic stem cells (ESCs) 8-fold more efficiently than triamterene

规格	价格	是否有货	数量
1mg		In-stock
5mg		In-stock
10mg		In-stock
50mg		In-stock
10 mM * 1 mL in DMSO		In-stock

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生物活性

Epiblastin A is an ATP competitive casein kinase 1 (CK1) inhibitor with IC₅₀s of 8.9, 0.5, and 4.7 µM for CK1α, CK1δ, and CK1 ɛ, respectively. Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition of CK1.

分子式

C₁₂H₁₀ClN₇

分子量

287.7

CAS号

16470-02-3

中文名称

Epiblastin A - Bio-X

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO: 4.55 mg/mL (15.81 mM; ultrasonic and warming and heat to 60°C)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.4757 mL	17.3786 mL	34.7572 mL
5 mM	0.6951 mL	3.4757 mL	6.9514 mL
10 mM	0.3476 mL	1.7379 mL	3.4757 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： ≥98%

Data Sheet

产品使用指南

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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Other Forms of Rapamycin:

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