ML-352
目录号 : KCM11873 CAS No. : 1649450-12-3 纯度 : ≥98%
ML-352 is a noncompetitive inhibitor of the presynaptic choline transporter (CHT) with K values of 92 and 166 nM for HEK293 cells expressing human CHT and mouse forebrain synaptosomes, respectively. It is selective for CHT over dopamine, norepinephrine, and serotonin transporters in HEK293 cells expressing human transporters when used at a concentration of 5 μM as well as a panel of 68 G protein-coupled receptors, ion channels, and transporters when used at a concentration of 10 μM. ML-352 (5 μM) increases cell surface expression of CHT without affecting total protein levels.
规格 价格 是否有货 数量
5mg
In-stock
10mg
In-stock
10 mM * 1 mL in DMSO
In-stock

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生物活性

ML352 is a noncompetitive inhibitor of the presynaptic choline transporter (CHT) with Ki values of 92 and 166 nM for HEK293 cells expressing human CHT and mouse forebrain synaptosomes, respectively.

分子式
C21H29N3O4
分子量
387.47
CAS号
1649450-12-3
中文名称
ML352 抑制剂
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶解性数据
In Vitro: 

DMSO: 250 mg/mL (645.21 mM; Need ultrasonic)

配制储备液
                                           
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
                                                                                                                    
1 mM 2.5808 mL 12.9042 mL 25.8084 mL
5 mM 0.516 mL 2.5808 mL 5.1617 mL
10 mM 0.2581 mL 1.2904 mL 2.5808 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

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