1,2,3,4-Tetrahydro-β-carboline - CAS:16502-01-5

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1,2,3,4-Tetrahydro-β-carboline (Synonyms:1,2,3,4-四氢-9H-吡啶[3,4-b]并吲哚; Tetrahydro-β-carboline; Tryptoline)

目录号 : KCM11877 CAS No. : 16502-01-5 纯度 : ≥95%

Data Sheet SDS 产品使用指南

1,2,3,4-Tetrahydro-β-carboline is a serotonin reuptake inhibitor (IC = 7.4 µM in rat brain homogenates) and metabolite of tryptamine . In vivo, 1,2,3,4-tetrahydro-β-carboline (20 and 40 µg/animal, i.c.v.) reduces serotonin levels in rat forebrain. It induces serotonin-mediated hyperactivity syndrome (HHS) in rats (ED = 48 mg/kg). 1,2,3,4-Tetrahydro-β-carboline (6.25-75 mg/kg) also reduces acetic acid-induced writhing in rats.

规格	价格	是否有货	数量
1g		In-stock
5g		In-stock
10 mM * 1 mL in DMSO		In-stock

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生物活性

1,2,3,4-Tetrahydro-β-carboline is a metabolite of tryptamine, also is a competitive serotonin reuptake inhibitor with an Ki value of 6.1 µM.

体内研究

1,2,3,4-Tetrahydro-β-carboline (20 µg; i.c.v.) increases the serotonin levels in the same part of the brain in rats.

Animal Model:	180-200g female Sprague-Dawley rats
Dosage:	20 µg
Administration:	Intraventricular injection
Result:	Increased of serotonin levels in the same part of the brain whereas the monoamine oxidase activity was not altered.

分子式

C₁₁H₁₂N₂

分子量

172.23

CAS号

16502-01-5

中文名称

1,2,3,4-四氢-9H-吡啶[3,4-b]并吲哚

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

2-8°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

DMSO: 100 mg/mL (580.62 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	5.8062 mL	29.0309 mL	58.0619 mL
5 mM	1.1612 mL	5.8062 mL	11.6124 mL
10 mM	0.5806 mL	2.9031 mL	5.8062 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： ≥95%