4-Methylumbelliferyl Palmitate - CAS:17695-48-6

您当前的位置：

4-Methylumbelliferyl Palmitate (Synonyms:4-甲基伞形基棕榈酸酯;4-甲基伞形酮棕榈酸酯;5-氯-3,4-二氢-1H-2-萘酮)

目录号 : KCM12009 CAS No. : 17695-48-6 纯度 : ≥98%

Data Sheet 产品使用指南

Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase. 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL). 4-MUP is cleaved by LAL to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. 4-MUP may also be cleaved by other acid lipases. Recent advances allow the assessment of LAL activity in very small blood volumes using 4-MUP.

规格	价格	是否有货	数量
100mg		In-stock
250mg		In-stock
500mg		In-stock
1g		In-stock

加入购物车大包装询价

Other Forms of Rapamycin:

X-Gluc cyclohexanamine In-stock
5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside In-stock
Nicotinamide 1,N6-ethenoadenine dinucleotide In-stock
6,7-Diethoxy-4-methylcoumarin In-stock
EDANS sodium In-stock

KKL Med 的所有产品和服务仅用于科学研究，不能被用于人体，兽医，我们也不向个人提供产品和服务。

生物活性

4-Methylumbelliferyl Palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl Palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions.

分子式

C₂₆H₃₈O₄

分子量

414.59

CAS号

17695-48-6

中文名称

5-氯-3,4-二氢-1H-2-萘酮

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据

In Vitro:

DMF : 50 mg/mL (120.60 mM; Need ultrasonic)

DMSO : 2 mg/mL (4.82 mM; ultrasonic and warming and heat to 60°C)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.4120 mL	12.0601 mL	24.1202 mL
5 mM	0.4824 mL	2.4120 mL	4.8240 mL
10 mM	0.2412 mL	1.2060 mL	2.4120 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： ≥98%