4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline (Synonyms:4-氯-6,7-双(2-甲氧基乙氧基)喹唑啉)
目录号 : KCM12135 CAS No. : 183322-18-1 纯度 : ≥95%
4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate. It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds. It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib , with antiproliferative activity.
规格 价格 是否有货 数量
5g
In-stock
10g
In-stock
25g
In-stock
50g
In-stock
100g
In-stock
10 mM * 1 mL in DMSO
In-stock

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生物活性

4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate, which can be used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer agents. 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline can also be used to synthesize EGFR inhibitors, including Erlotinib, with antiproliferative activity.

分子式
C14H17ClN2O4
分子量
312.75
CAS号
183322-18-1
中文名称
4-氯-6,7-双(甲氧基乙氧基)喹唑啉酮
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

DMSO: 50 mg/mL (159.87 mM; Need ultrasonic)

配制储备液
                                           
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
                                                                                                                    
1 mM 3.1974 mL 15.9872 mL 31.9744 mL
5 mM 0.6395 mL 3.1974 mL 6.3949 mL
10 mM 0.3197 mL 1.5987 mL 3.1974 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2