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ML-179
目录号 : KCM12220 CAS No. : 1883548-87-5 纯度 : ≥98%
Data Sheet 产品使用指南
ML-179 is a potent inverse agonist of liver receptor homolog-1 (LRH-1) (IC = 320 nM) with maximum efficacy of 40% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A and A, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC = 2.12 µM).
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1mg
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5mg
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10mg
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25mg
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分子式
C21H25F3N4O2
分子量
422.4
CAS号
1883548-87-5
中文名称
3-cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-2,4(1H,3H)-pyrimidinedione
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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