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Ac-DEVD-pNA
目录号 : KCM12235 CAS No. : 189684-50-2 纯度 : ≥95%
Data Sheet 产品使用指南
During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-pNA is a para-nitro aniline chromophore cleaved by caspases (K = 18, 11, 32, 180, and 12 µM for caspases-1, -3, -4, -6, and -7, respectively). It is not cleaved by caspase-2. Cleavage is monitored colorimetrically at 405 nm.
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生物活性
Ac-DEVD-pNA is a peptidic substrate of caspase-3/7.
分子式
C26H34N6O13
分子量
638.58
CAS号
189684-50-2
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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