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Atazanavir (Synonyms:阿扎那韦;阿扎那韦标准品;阿扎那韦硫酸盐;苄氧羰基-O-叔丁基-D-酪氨酸二环己基铵盐;阿扎那韦双硫酸盐;阿札那韦;阿扎那韦杂质;阿扎那韦游离碱;阿扎那韦手性异构体;阿扎那韦对映异构体;阿扎那韦(标准品);阿扎那韦中间体杂质1;阿扎那韦手性异构体3)
目录号 : KCM12342 CAS No. : 198904-31-3 纯度 : ≥95%
Data Sheet SDS 产品使用指南
Atazanavir is an azapeptide inhibitor of HIV-1 protease (K = 2.66 nM). It has antiviral activity against a variety of HIV-1 strains in several cell types with EC values ranging from 2.62 to 5.28 nM. Atazanavir exhibits a minor synergistic effect when used in combination with the reverse transcriptase inhibitor zidovudine in HIV-1-infected human peripheral blood mononuclear cells (PBMCs) and an additive effect when used in combination with several additional reverse transcriptase or HIV-1 protease inhibitors. Atazanavir also inhibits UDP-glucuronyltransferase 1A1 (UGT1A1), which is involved in bilirubin clearance. Formulations containing atazanavir have been used in combination therapy for the treatment of HIV-1 infection.
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1mg
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5mg
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分子式
C38H52N6O7
分子量
704.9
CAS号
198904-31-3
中文名称
阿扎那韦
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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