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4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (Synonyms:4-甲基香豆素基-β-D-吡喃半乳糖苷-6-硫酸钠盐;4-甲基-7-[(6-O-磺基-beta-D-吡喃半乳糖基)氧基]-2H-1-苯并吡喃-2-酮单钠盐)
目录号 : KCM12457 CAS No. : 206443-06-3 纯度 : ≥98%
Data Sheet SDS 产品使用指南
4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.
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分子式
C16H17O11S.Na
分子量
440.4
CAS号
206443-06-3
中文名称
4-甲基香豆素基-β-D-吡喃半乳糖苷-6-硫酸钠盐
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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