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4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside (Synonyms:4-甲基-7-[[6-S-(1-氧代十六烷基)-6-硫代-BETA-D-吡喃葡萄糖基]氧基]-2H-1-苯并吡喃-2-酮;4-甲基香豆素基-6-硫-十六酰基-β-D-吡喃葡萄糖苷)
目录号 : KCM12772 CAS No. : 229644-17-1 纯度 : ≥95%
Data Sheet SDS 产品使用指南
4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. 4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is cleaved by PPT/CLN1 to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. This substrate is used in assays that measure PPT activity, which is commonly deficient in the neurodegenerative disorder known as infantile neuronal ceroid lipofuscinosis.
规格 价格 是否有货 数量
500μg
In-stock
1mg
In-stock
5mg
In-stock
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分子式
C32H48O8S
分子量
592.8
CAS号
229644-17-1
中文名称
4-甲基香豆素基-6-硫-十六酰基-β-D-吡喃葡萄糖苷
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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