C16 Ceramide (d18:1/16:0) - CAS:24696-26-2

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C16 Ceramide (d18:1/16:0)

目录号 : KCM12942 CAS No. : 24696-26-2 纯度 : ≥98%

Data Sheet 产品使用指南

C16 Ceramide is a sphingolipid. It incorporates into the mitochondrial outer membrane and forms channels that increase its permeability. C16 Ceramide levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis. It accumulates in the lungs of patients with cystic fibrosis compared with the lungs of patients with pulmonary hypertension. Plasma levels of C16 ceramide are also increased in patients with acute coronary syndrome, and an increased plasma ratio of C16 to C24:0 ceramide is associated with major adverse cardiac events. It is also increased in tumor tissue from patients with breast cancer and is associated with metastatic cancer.

规格	价格	是否有货	数量
1mg		In-stock
5mg		In-stock
10mg		In-stock
25mg		In-stock

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分子式

C₃₄H₆₇NO₃

分子量

537.9

CAS号

24696-26-2

中文名称

N-棕榈酰神经鞘氨醇

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMF : 20 mg/mL (37.18 mM; ultrasonic and warming and heat to 60°C)

Ethanol : 10 mg/mL (18.59 mM; ultrasonic and warming and heat to 60°C)

DMSO : < 1 mg/mL (ultrasonic) (insoluble or slightly soluble)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.8591 mL	9.2954 mL	18.5908 mL
5 mM	0.3718 mL	1.8591 mL	3.7182 mL
10 mM	0.1859 mL	0.9295 mL	1.8591 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： 10% EtOH → 90% corn oil

Solubility:≥ 2 mg/mL (3.72 mM); Clear solution

此⽅案可获得 ≥ 2 mg/mL (3.72 mM，饱和度未知) 的澄清溶液，此⽅案不适⽤于实验周期在半个⽉以上的实验。

以 1 mL ⼯作液为例，取 100 μL 20.0 mg/mL 的澄清 EtOH 储备液加到 900 μL ⽟⽶油中，混合均匀。