SE 175
目录号 : KCM13018
CAS No. : 258278-64-7
纯度 : ≥97%
SE 175 is an organic nitrate compound of the same general class as nitroglycerin. These nitrate compounds can act as NO-donors in vivo following reductive transformation of the nitrate group to nitric oxide. The nitroxyacylated thiosalicylates, such as SE 175, were developed in an effort to facilitate this reductive process and accelerate the release of NO. SE 175 is stable in buffer or saline solution. In the intact rat, it stimulates endothelial soluble guanylate cyclase and induces aortic vasorelaxation with an EC of 20 µM, which is intermediate in potency between nitroglycerine and isosorbide dinitrate.
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| 分子式 |
C16H13NO6S
|
| 分子量 |
347.3
|
| CAS号 |
258278-64-7
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|