N-(4-acetamidophenyl)-Indomethacin amide
(Synonyms:N-(4-乙酰氨基苯基)吲哚美辛氨化物;N-(4-乙酰氨基苯基)吲哚美辛酰胺;苯基 2,3,4,6-O-四乙酰基-ALPHA-D-硫代吡喃甘露糖苷)
目录号 : KCM13039
CAS No. : 261766-23-8
纯度 : ≥98%
N-(4-acetamidophenyl)-indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2. N-4-AIA inhibits human recombinant and ovine COX-2 with IC values of 0.12 and 0.625 µM, respectively. It is about 400 times less potent as an inhibitor of human recombinant COX-1 and 80 times less potent as an inhibitor of ovine COX-1 than ovine COX-2.
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| 分子式 |
C27H24ClN3O4
|
| 分子量 |
490
|
| CAS号 |
261766-23-8
|
| 中文名称 |
苯基 2,3,4,6-O-四乙酰基-ALPHA-D-硫代吡喃甘露糖苷
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|