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N-(3-pyridyl)-Indomethacin amide
目录号 : KCM13040 CAS No. : 261766-29-4 纯度 : ≥98%
Data Sheet 产品使用指南
N-(3-pyridyl)-indomethacin amide (N-3PyIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2. N-3PyIA selectively inhibits human recombinant COX-2 with an IC of 0.052 µM. It is about 1,300 times less potent as an inhibitor of ovine recombinant COX-1. However, N-3PyIA is not selective as an inhibitor of ovine seminal vesicular COX-1 and ovine placental COX-2. The IC values for ovine COX-1 and -2 are 75 and 50 µM, respectively.
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5mg
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10mg
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50mg
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分子式
C24H20ClN3O3
分子量
433.9
CAS号
261766-29-4
中文名称
2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-(3-pyr idinyl)acetamide
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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