Azelaoyl PAF
目录号 : KCM13484
CAS No. : 354583-69-0
纯度 : ≥98%
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ. One of these substances was recently isolated and purified from oxLDL, and identified as azelaoyl PAF. Azelaoyl PAF is a potent PPARγ agonist which competes for the thiazolidinedione binding site. Azelaoyl PAF is more potent than 15-deoxy-Δ-prostaglandin J, and equipotent with rosiglitazone as a ligand for this receptor.
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| 分子式 |
C33H66NO9P
|
| 分子量 |
651.9
|
| CAS号 |
354583-69-0
|
| 中文名称 |
[(2R)-2-(8-carboxyoctanoyloxy)-3-hexadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|